Additionally, inhibition of Pim-1 kinase in peripheral T-cell lymphoma cells resulted in decreased levels of diverse DNA repair proteins, including ERCC8, which is involved in NER, XRCC2, involved in HR, and XRCC5, involved in C-NHEJ, associated with increased γ-H2AX levels, consistent with increased DNA damage due to decreased levels of DNA repair proteins [31]. Here, XRCC5 is linked to peripheral T-cell lymphoma, not otherwise specified.