VLDLR and obesity due to melanocortin 4 receptor deficiency: In light of the finding that adoptive transfer of bone marrow cells from VLDLR knockout mice into wild-type mice relieved adipose tissue inflammation and improved insulin resistance in DIO in mice due to reduced TG and ceramides uptake into ATM [46], certain subsets of ATM could be new pharmacological targets in obesity-related inflammation and metabolic complications, which warrants further investigation.