However, there were also HLA-I phosphopeptides that elicited higher responses in CRC patients than their healthy counterparts (Figures 4B, C, open green circles), some significantly so - namely RAHSsPASL (p=0.032) a peptide from transcriptional coactivator YAP1, from the TGFβ signaling pathway (Figure S4) and TRKtPESFL (p=0.036) a peptide from Epsin-1. The gene discussed is YAP1; the disease is colorectal carcinoma.