During myocardial ischemia-reperfusion, cardiomyocytes release IL-6, which induces neutrophils and cardiomyocytes to express CD11b/CD18 and intercellular adhesion molecule-1 (ICAM-1), thereby damaging the myocardium (Gwechenberger et al., 1999). Here, ICAM1 is linked to myocardial ischemia.