The biological significance of CK7, relative to the progression of CRC, can be seen in our results; the P-value observed in the Kaplan–Meier analysis using a cut-off value of 10% was lower (rmean survival 4.98 vs. 7.74 years, P = 0.007) than using 1% as the cut-off (rmean survival 5.79 vs. 7.74 years, P = 0.036); notwithstanding, the latter analysis contained more cases regarded as CK7 + (18 and 28 CK7 + probands, respectively). The gene discussed is KRT7; the disease is colorectal carcinoma.