Among the enriched genes, ANK1, AvBD1, ACTN2, ADA, C7, CATH2, CCND3, CSF3R, EDN2, JUN, TF, RHAG, S100A9, SERPINB10, SSTR2, AvBD2, EPB42, LECT2, LYG2, PTPRC and STOM were upregulated in the FHS-affected group. The gene discussed is ANK1; the disease is Floating-Harbor syndrome.