Considering the top 9 DE genes, those related to collagen (COL13A1), myosin (MYH15), phosphatases (PSPH) and transferases (GGT1) were downregulated, while genes involved with response to microorganisms and immune system were upregulated in the FHS-affected group (Table 2). The gene discussed is MYH15; the disease is Floating-Harbor syndrome.