The results of the NetworkAnalyst platform indicates associations between DE genes and Wnt signaling pathway, GnRH signaling pathway, Adrenergic signaling in cardiomyocytes, VEGF signaling pathway, Bacterial infection, Focal adhesion, Gap junction, Toll-like receptor signaling pathway, AGE-RAGE signaling pathway in diabetic complications and NOD-like receptor signaling pathway (Fig. 2). The gene discussed is GNRH1; the disease is bacterial infectious disease.