VEGFA and breast cancer: ZFP36L1 expression has been reported to play an important role in breast cancer growth and progression by regulating cell cycle progression, hypoxia-associated signaling33 and tumor angiogenesis34, where intratumoral injection of an active truncated form of ZFP36L1 in a rodent model of breast cancer led to reduced tumor vascular endothelial growth factor expression, vascularization and growth34.