TP53 and posterior cortical atrophy: Interestingly, miR-642a-5p’s ability to reduce cell viability of PCa cells is not reliant on cellular p53 status, as our previous study using other PCa cell subtypes which harbour non-functional p53 (e.g. DU145) also showed a reduction in cell viability with miR-642a-5p overexpression25,30.