DOCK3 and Parkinson disease: CNFD was positively associated with MoCA (Spearman’s correlation coefficient r = 0.683, P < 0.001), but negatively associated with UPDRS-III (Pearson’s correlation coefficient r = −0.481, P < 0.001) and total UPDRS scores (Pearson’s correlation coefficient r = −0.401, P = 0.001) in PD patients (Fig. 4).