Previous studies reported that MSCs from different origins could alleviate Con A-induced hepatitis by acting on different types of immune cells, including switching Con A-stimulated macrophages to the M2 phenotype by bone marrow-derived MSCs [29], suppression of myeloid-lineage cells and CD4+ T cell by adipose-derived MSCs [32], suppression of T cells by both bone marrow-derived MSCs and tonsil-derived MSCs [28, 31], and suppression of NKT cells by bone marrow-derived MSCs [26, 30]. Here, CD4 is linked to Hepatitis.