MALAT1 and acute kidney injury: Interestingly, data from different teams suggest that targeting LncRNA MALAT1 is a novel strategy to attenuate LPS-induced inflammatory responses and AKI [35], LncRNA MALAT1 regulates high-glucose induced cell pyroptosis in endothelial and epithelial cells [21,28], and LncRNA MALAT1 is closely associated with renal ischemia-reperfusion injury and inflammation [47].