Although it was previously reported that SCRIB was universally overexpressed in cells of various tumors including colon, liver, prostate, uterus, thyroid, lung, bladder, breast, ovary, and stomach [46], some studies have reported a down-regulation and cytoplasmic localization of SCRIB in colon, endometrial, breast, and cervical cancers [43]. The gene discussed is SCRIB; the disease is cervical carcinoma.