Tagliafico et al. provided similar results using digital breast tomosynthesis imaging in their series of 70 women diagnosed with invasive breast carcinoma; tumour sphericity, autocorrelation (grey level co-occurrence matrix), interquartile range, robust mean absolute deviation, and short-run high grey-level emphasis all show an association with Ki-67 expression [156]. The gene discussed is MKI67; the disease is invasive breast carcinoma.