MKI67 and neoplasm: Baseline levels of Ki-67 expression in TNBC are expected to be higher than in Luminal tumours [71], and definitions of cut-offs within triple negative disease are diverse and inconsistent, withreported values of as low as 10% and as high as 35% within TNBC disease [72,73], and a recent meta-analysis of 35 independent studies of almost 8000 patients with resected TNBC suggests a cut-off of 40% is associated with a greatest risk of disease recurrence and mortality [74] (Table 1).