We first compared OS between patients with and without any PV (Figure 2D, left) and, secondly, with a PV in the genes coding for proteins involved in DDSB repair via HR pathway (ATM, BRCA1/FANCS, BRCA2/FANCD1, BRIP1/FANCJ, ERCC4/FANCQ, FANCE, FANCG, and PALB2/FANCN) and with PV in other non-HR genes (CHEK2, HOXB13, NBN, POLD1, and TP53), respectively (Figure 2D, right). The gene discussed is ATM; the disease is acquired polycythemia vera.