CD274 and neoplasm: Although we determined ICS (percentage of the area of PD-L1-positive infiltrating immune cells in respect to the total area of the tumor tissue) instead of IC% (proportion of membranous positive PD-L1 immune cells based on the total immune cell population) [29], which is therefore not equivalent to ICS by definition [10], we similarly observed that the automated determination of ICS such as IC% was worse than the TPS in agreement to human values [29].