HSP90B2P and nasopharyngeal carcinoma: Interestingly, Cai et al. described prognostic significance of HSP70 in nasopharyngeal carcinoma depending on cellular compartmentalization of HSP expression: both membranous and cytoplasmic positivity improved prognosis in a relatively large cohort of patients (n = 507) whilst nuclear positivity showed negative impact on survival, with strikingly strong statistical significance [63].