PDX1 and pancreatic neoplasm: In our earlier work [7], we showed that expression of the embryonic pancreas lineage-specific transcription factor, pancreatic and duodenal homeobox 1 (PDX1), in the pancreatic cancer cell line, PANC-1, leads to a decrease in motility of cells and suppression of their ability to spread throughout the body in the model organism Danio rerio.