ITGAV and gastric cancer: Thus, in cells expressing PDX1, there was an increase in the expression level of the gene 5 alpha subunit of integrin (integrin subunit alpha V), reported to stimulate proliferation, migration, and invasion of gastric cancer cells [30], and an increase in the expression level of integrin subunit beta 8, a positive regulator of cell migration, since ITGB8 knockdown leads to a reduction in cell motility [31].