Although different median TRBC1+/TRBC1− ratios were found among cells expressing each of the TCRVβ families identified (especially in reactive cases), TRBC1 expression appeared to be independent of the specific TCRVβ family expressed among HD, as well as HDc and reactive lymphocytosis patients, i.e., a bimodal pattern was found for all families. Here, TRBC1 is linked to Huntington disease.