IAP family members include Survivin, X-linked inhibitor of apoptosis (XIAP), inhibitors of apoptosis 1 and 2 (c-IAP1 and c-IAP2), BIR-repeat-containing ubiquitin-conjugating enzyme (BRUCE/Apollon), neuronal apoptosis inhibitor protein (NAIP), IAP-like protein 2 (ILP-2) and melanoma IAP (ML-IAP/Livin) [62]. This evidence concerns the gene XIAP and melanoma.