Another network that stands out, albeit a smaller one, is highly concentrated around miR-34a [76] and comprises heavy-weight cancer genes, namely TP53 and MYC, together with some other outstanding oncoproteins, such as MYCN, NOTCH1, WNT1, CSF1R, CDC34 and the stem cell regulator NANOG (Figure 3). The gene discussed is NOTCH1; the disease is cancer.