Sun et al. investigated the promoting effect of calcitriol on the miR-627 expression and demonstrated a relation between the suppression of its target, cytochrome P450 family 3 subfamily A member 4 (CYP3A4), and the CPT11 sensitivity in CRC cells with a relative inhibition of cell growth and an increase of apoptosis [47]. The gene discussed is CYP3A4; the disease is colorectal carcinoma.