Besides these, Glypican 3 (GPC3) [77], cytokeratin 19 (CK19) [78], Golgi protein 73 (GP73) [79], osteopontin [80], squamous cell carcinoma antigen (SCCA) [81] and annexin A2 [82] have all been shown to have diagnostic and prognostic roles in HCC as well, but they have not been validated sufficiently for routine clinical use [20]. Here, GPC3 is linked to hepatocellular carcinoma.