IMP3 and neoplasm: Precisely because of the above-mentioned facts, the goals of our study were (i) to determine the expression of IMP3 in benign laryngeal lesions, low and high-grade dysplasia, and LSCC; (ii) correlate its expression with other markers of cell growth and proliferation (Ki-67, p53 and cyclin D1); (iii) determine pathological–clinical features of the tumor with IMP3 overexpression and (iv) its influence on disease outcome of patients with laryngeal squamous cell carcinoma.