These include the chemical carcinogen urethane-induced NSCLC model in mice [25,26] and the oncogene-induced NSCLC, such as mutant oncogenic KRAS [11,12,13,14] and EGFR [15,16,17], both in mouse NSCLC transgenic models and in human NSCLC cell lines transplanted in immune-compromised mice. This evidence concerns the gene EGFR and non-small cell lung carcinoma.