The activation of P2X7 receptors can promote the proliferation and growth of human pancreatic cancer cells by increasing the phosphorylation of ERK1/2 and JNK [12]; P2X7 can also inhibit the migration of breast cancer-derived endothelial cells by activating the cAMP signaling pathway [13]. The gene discussed is P2RX7; the disease is pancreatic neoplasm.