Similarly, in the human colon cancer SW480 and HCT116 cell lines, MAGI1 overexpression stabilizes E-cadherin localization at cell–cell junctions, enhances actin stress fiber, and focal adhesion formation, increases cell adhesion to matrix proteins, and suppressed anchorage-independent growth, migration, and invasiveness [148]. This evidence concerns the gene MAGI1 and colonic neoplasm.