In contrast, other studies evidenced increased MAGI2 immunostaining in high-grade prostatic intraepithelial neoplasia (HGPIN) and tumor, as compared with control tissue [151,152,153,154,155], with a decreased expression during progression from HGPIN to adenocarcinoma of low to high Gleason score [151]. Here, MAGI2 is linked to adenocarcinoma.