PTEN and breast cancer: In breast cancers, miR-487a was positively correlated with lymph nodes metastasis and negatively correlated with the expression of MAGI2. At the mechanistic level, miR-487a is transactivated by the TGF-β /NFκB signaling pathways and promotes epithelial–mesenchymal transition (EMT) and invasiveness via targeting MAGI2/ PTEN axis [139].