Although SHEP-2 and SK-N-AS cells were shown to express relatively low levels of SIRPα on their surface (Figure S3C,D), no neutrophil-cytotoxicity effect was detected in the conditions with anti-SIRPα treatment only, suggesting that the level of opsonization that the anti-SIRPα antibodies could possibly cause on the tumor cells is not sufficient to trigger neutrophil killing by itself. The gene discussed is SIRPA; the disease is neoplasm.