KLK3 and posterior cortical atrophy: The Stockholm3 score predicts the probability of GS > 6 on systematic and targeted biopsy using a combination of 5 plasma biomarkers (total PSA, free PSA, hK2, Macrophage inhibitory cytokine-1 [MIC-1], microseminoprotein-beta [MSMB]), 101 germline genetic markers, and 5 clinical variables (age, first-degree family history of PCa, a previous biopsy, DRE, and prostate volume assessed by transrectal ultrasound at PCa diagnosis) [31,57].