Particularly, light-induced activation of ChR2 dopaminergic neurons in the genetic model Drosophila larva rescues PD symptoms caused by α-synuclein [141], light-dependent activation of mitochondrially expressed proton pump dR reinforces mitochondrial function and prevents α-synuclein-driven mitochondrial dysfunction in a Drosophila model of PD [142]. The gene discussed is SNCA; the disease is Parkinson disease.