Among the proteins containing Keap1-interacting region (KIR)-like ETGE motifs, which compete with the Nrf2 in binding to Keap1, are p62/sequestosome 1 (SQSTM1), dipeptidyl peptidase 3 (DPP3), the Wilms tumor gene on the X chromosome (WTX) and a partner and localizer of BRCA2 (PALB2) [53]. This evidence concerns the gene KEAP1 and neoplasm.