Unique among the top 20 up- and down-regulated proteins in SOMAscan® GBM proteomes, the Human Protein Atlas identified high MDK expression as a predictive marker of poor prognosis in GBM (https://www.proteinatlas.org/ENSG00000110492-MDK/pathology/glioma, accessed on 5 January 2021). This evidence concerns the gene MDK and central nervous system cancer.