CSF1 and neoplasm: As CSF1 and FGF signals are both involved in the accumulation of tumor-infiltrating/promoting MDSCs and M2-TAMs, the dual inhibition of FGF and CSF1 or VEGF signaling is expected to enhance antitumor effects through the targeting of immune evasion and angiogenesis in the TME [23,24,25,26,30,38,39,40,41,44].