We correlated these percentages with the percentages of Ki67+ cells within total RTE-Tregs/Tresps, MN-Tregs/Tresps, CD31+-memory-Tregs/Tresps and CD31−-memory-Tregs/Tresps to see which pathways were strengthened with age, or in case of SLE, were intensified or already exhausted regardless of age. Here, MKI67 is linked to systemic lupus erythematosus.