We correlated these percentages with the percentages of Ki67+ cells within total RTE-Tregs/Tresps, MN-Tregs/Tresps, CD31+-memory-Tregs/Tresps and CD31−-memory-Tregs/Tresps to see which pathways were strengthened with age, or in case of SLE, were intensified or already exhausted regardless of age. This evidence concerns the gene PECAM1 and systemic lupus erythematosus.