They evaluated the DNA methylation levels at PR domain-containing protein 16 (PRDM16), bone morphogenetic protein 7 (BMP7), C-terminal binding protein 2 (CTBP2) and peroxisome proliferator-activated receptor-gamma co-activator 1 alpha (PPARGC1α) gene loci in the fetal side of placentas from 133 women (33 with GDM) followed during pregnancy (one visit at the end of each trimester), and observed that only BMP7 DNA methylation levels were lower in GDM compared to NGT. Here, PRDM16 is linked to gestational diabetes.