In the liver, HuR is upregulated in HCC patients and increases the expression of transcripts involved in cell cycle regulation (i.e., cyclin A and D1) [144], inhibits apoptosis through direct interaction with the FAS mRNA and by inhibiting caspase-3 activity [144,145], and facilitates hepatocyte de-differentiation by stabilizing the MAT2A transcript [146]. The gene discussed is ELAVL1; the disease is hepatocellular carcinoma.