For example, PRMT1, a protein arginine methyltransferase overexpressed in HCC, promotes carcinogenesis, but in the meantime, methylates UBAP2L on the RGG motif, thereby inhibiting SG formation [40,48,49,50] and thus questioning the necessity to assemble SGs for the oncogenic functions of UBAP2L. Here, UBAP2L is linked to hepatocellular carcinoma.