STAT6 expression has also been reported in dedifferentiated liposarcoma and GLI1-amplified tumors; hence, in cases with overlapping morphology and STAT6 immunoreactivity, additional molecular studies are needed to establish a definitive diagnosis [2,15,16,17,18,19,20,21,22,23,24,25,33,34,35,36,37,38,39,40,41,42]. Here, STAT6 is linked to liposarcoma.