However, we identified DMRs within three genes that contained a differentially methylated CpG reported by Kulis et al. [23]: BCL9L, MYB, and NCOR2. The CpGs and DMRs within these genes had the same direction of the methylation change; they were hypomethylated in CLL with SF3B1mut compared to CLL with SF3B1WT. This evidence concerns the gene MYB and B-cell chronic lymphocytic leukemia.