CSNK1A1 and myelodysplastic syndrome associated with isolated del(5q): For example, different mouse models of 5q− syndrome have been generated via deletion of a large chromosome interval syntenic to human 5q33.1, including Rps14, or co-deletion of Rps14 with three other 5q− syndrome genes (Csnk1a1/miRNA145/miRNA146a) [49,138].