NFKB1 and cancer: In our previous work, we have already identified Anxa2 as a cellular target of (20S) ginsenoside Rh2((20S)G-Rh2), a natural ginseng extract with anti-cancer activity, and (20S)G-Rh2 inhibited NF-κB activation by interfering Anxa2-NF-κB p50 subunit interaction [27,28].