ALDH3A2 and acute myeloid leukemia: Based on findings that oncogenic mutations alter the metabolic environment in tumor cells, Yusuf et al. [50] revealed a unique dependence on aldehyde dehydrogenase 3 family member A2 (Aldh3a2), which oxidizes long-chain aliphatic aldehydes, and vulnerability in different murine and human acute myeloid leukemia (AML) cells.