A notable recent report by our team showed that MPSE pretreatment before irradiation in breast cancer cells inhibits the radiation induced epithelial to mesenchymal transition (EMT) process and confers radiosensitivity, probably by attenuating the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) and mitogen-activated protein kinase (MAPK) pathways [19]. This evidence concerns the gene AKT1 and breast cancer.