It is interesting that we also found a consistent decreased expression of two circRNAs in the entorhinal cortex of AD female patients, i.e., hsa_circ_0006916 and hsa_circ_0073127; hsa_circ_0006916 was first described as a circRNA derived from the synaptic HOMER1 gene [23]. The gene discussed is HOMER1; the disease is Alzheimer disease.