For the purpose of this study, we selected three circRNAs from circInteractome [27], hsa_circ_0006916 and hsa_circ_0073128, which had been previously described in AD brains [24,26], and hsa_circ_0073127, which arises from exons 7 and 8 that are not included in the HOMER1A linear transcript. This evidence concerns the gene HOMER1 and Alzheimer disease.