According to the THBS4 expression data in the colon adenocarcinoma (COAD) in the Cancer Genome Atlas (TCGA), although it showed THBS4 is not a prognostic marker in COAD, there seems to be a strong relationship between stage of disease, expression levels and/or survival rate and survival rate is significantly lower in the higher expression individuals [207]. The gene discussed is THBS4; the disease is colon adenocarcinoma.