NPM1 and acute myeloid leukemia: Furthermore, Narayan et al. utilized NetMHC to investigate HLA class I binding affinities for putative 9–11 mer peptides spanning common recurrent AML mutations and computationally documented that several NPM1-mutated peptides, including mutation-bearing sequences AIQDLCLAV and AVEEVSLRK, are predicted to efficiently bind various HLA class I alleles [21].