NPM1 and acute myeloid leukemia: Relevant to the allogeneic HSCT context, in a patient affected with NPM1-mutated AML in molecular relapse after allogeneic HSCT, described by a German group, preemptive DLI induced polyspecific CD8+ T cells responses directed to different LAA, including #1 and #3 NPM1-mutated peptides, which contributed to achievement of MRD negativity, thereby suggesting a correlation between GvL and LAA-specific CTL response [58].