EYS and retinitis pigmentosa 1: In order to investigate the therapeutic potential of exon skipping for the future treatment of EYS-associated RP, we generated and characterized a stable zebrafish line from which the region containing the orthologous exons of the frequently mutated human EYS exons 37-41, zebrafish eys exons 40-44, was specifically excised from the genome using the CRISPR/Cas9 system.