When stimulated under M1 macrophage polarizing conditions (LPS/IFNγ), monocytes from people with CAD showed a greater gene expression of inflammatory cytokines (IL-6 and IL-1β) compared to controls [35], though another study found little difference in cytokine release between CAD and controls [20] (Table 2). The gene discussed is IFNG; the disease is coronary artery disorder.