Thus, apart from the fact that the probability of suffering a stroke is double in women than in men, this considerable difference in participation may be due to the fact that women have to overcome specific challenges to participate in the CRP, including playing the role of informal caregivers (children, grandchildren, a relative dependent on them in the household), being on-demand for multiple roles, having a negative body image, lack of previous experience with exercise, and limited cultural support for physically active lifestyles [24]. The gene discussed is CRP; the disease is Stroke.