Examination of the distribution of the cardiac ACE2 expression levels in dilated cardiomyopathy and hypertrophic cardiomyopathy has affirmed downregulation of ACE2 expression in fibroblasts, pericytes, and vascular smooth muscles with a concomitant upregulation of ACE2 expression in cardiomyocytes [72]. This evidence concerns the gene ACE2 and hypertrophic cardiomyopathy.