In patients who became septic within 24 h of admission (n = 29), the median PCT value was 0.49 μg/L (0.16–2.24 μg/L), while PCT was lower in patients who developed sepsis more than 24 h after admission to the ED (n = 17; median PCT: 0.14 μg/L; IQR: 0.10–2.50 μg/L; p < 0.001) (Supplementary Figure S3). Here, CALCA is linked to Sepsis.