A high frequency of hemostatic abnormalities, including Hb, platelet count, PT-INR, and D-dimer abnormalities, suggests that a coagulopathy similar to thrombotic microangiopathy (TMA) [23] with disseminated intravascular coagulation (DIC) [24] may occur in patients with severe COVID-19. This evidence concerns the gene GSTM1 and thrombotic microangiopathy.