Considering that STZ is transported into beta cells via GLUT2, the increased population of Ppy-lineage beta cells in the islets of mice with STZ-induced diabetes is thought to correspond to the Ppy-lineage beta cells with low expression of Slc2a2/GLUT2 observed by scRNA-seq analysis and immunohistochemistry. Here, SLC2A2 is linked to diabetes mellitus.